FIELD: medicine.
SUBSTANCE: what is described is an antibody molecule which selectively binds with a cellular surface ICAM-1 and if bound with ICAM-1, induces apoptosis in a target cell, and a nucleic acid molecule coding said antibody. Also, methods and pharmaceutical compositions for apoptosis induction and application thereof are presented.
EFFECT: invention allows producing molecules for cell apoptosis induction.
33 cl, 11 dwg, 3 tbl, 6 ex
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