METHOD FOR TREATING LOCAL METASTATIC MALIGNANT TUMORS OF NASAL CAVITY, PERINASAL ANTRA AND NASOPHARYNX Russian patent published in 2005 - IPC

FIELD: medicine, oncology.

SUBSTANCE: the method deals with polychemotherapy and is fulfilled by the following technique: it is necessary to carry out blood sampling in these patients at the quantity of 25 ml: during the 1^st d of polychemotherapy one should incubate 5 ml autoblood with 50 mg/sq. m metothrexate, during the 2^nd, 3d, 4^th and 5^th d one should incubate per 5 ml autoblood with 15 mg/sq. m bleomycin daily in thermostat at 37 C for 30 min, carry out application anesthesia and introduce chemopreparations upon autoblood into endonasal tumor component or alternate intratumor introduction of chemopreparations upon autoblood at introducing them into maxillary antrum if it is affected with tumor process. The method provides local concentration and decreased toxicity of chemopreparations due to their intratumor introduction upon autoblood.

EFFECT: higher efficiency of therapy.

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