METHOD OF TREATING RECURRENT NASOPHARYNX CANCER Russian patent published in 2011 - IPC A61N5/10 A61K35/28 A61K31/282 A61K31/704 A61K31/513 A61K38/02 A61P35/00 

Abstract RU 2420333 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used for treating patients with recurrent nasopharynx cancer. The method involves administration of chemopreparations and gamma-ray teletherapy; the first therapeutic day involves intravenous drop infusion of an automyelosuspension ex temporae incubated with cisplatin at 50 mg/m2 with underlying excessive hydration and forced diuresis; 5-fluorouracil dissolved in normal saline 200 ml is infused the same day at 500 mg/m2. After one day of a pause, gamma-ray teletherapy is performed in a hyperfractionation mode taking into account a residual dose 1.5 Gy of single basic dose twice a day every 5 hours to at 5 o'clock to 65 isoGy of total basic dose. After one week of a pause, the second course of automyelochemotherapy with cisplatin at 100 mg/m2 with underlying excessive hydration and forced diuresis is performed; 5-fluorouracil 500 mg/m2, bleomycine 30 mg/m2 and adriamycin 35 mg/m2 are infused the same day.

EFFECT: use of the invention allows higher clinical effectiveness ensured by combined anticancer effect of the chemopreparations and additional stimulation of immune cells by the factors contained in the bone marrow.

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RU 2 420 333 C2

Authors

Sidorenko Jurij Sergeevich

Dzhabarov Farkhad Rasimovich

Frantsijants Elena Mikhajlovna

Rozenko Ljudmila Jakovlevna

Kolycheva Elena Viktorovna

Dates

2011-06-10Published

2009-08-17Filed