FIELD: medicine, immunology, nucleic acids.
SUBSTANCE: invention relates to a method for stimulation of the immune response using nucleic acids-containing immunostimulating compositions, oligonucleotide-containing composition and to a method for treatment or prophylaxis of allergy or asthma. For stimulation of the immune response thymidine-enriched nucleic acid comprising poly-T sequences and/or comprising above 60% of thymidine-containing nucleotide residues is administrated. Invention provides the development of new method for stimulation of the immune response due to administration of the proposed immunostimulating nucleic acid.
EFFECT: valuable medicinal properties of nucleic acid.
27 cl, 12 dwg, 12 ex
Title | Year | Author | Number |
---|---|---|---|
IMMUNOSTIMULATING PHOSPHOROTHIOATE CpG-OLIGONUCLEOTIDES, CONTAINING PHOSPHODIESTER LINKS, METHOD OF IMMUNOMODULATION, METHOD OF IMMUNE RESPONSE STIMULATION | 2003 |
|
RU2338750C2 |
CPG-OLIGONUCLEOTIDE ANALOGUES, CONTAINING HYDROPHOBIC T-ANALOGUES WITH AMPLIFIED IMMUNOSTIMULATORY ACTIVITY | 2007 |
|
RU2477315C2 |
SEMI-SOFT C-CLASS IMMUNOSTIMULATORY OLIGONUCLEOTIDES | 2005 |
|
RU2393223C2 |
IMMUNOSTIMULATING OLIGONUCLEOTIDES | 2009 |
|
RU2477753C2 |
IMMUNOSTIMULATORY OLIGONUCLEOTIDES | 2012 |
|
RU2610690C2 |
IMMUNOSTIMULATING G,U-CONTAINING OLYGORIBONUCLEOTIDES | 2003 |
|
RU2302865C2 |
CONJUGATES OF PEPTIDE Melan-A, VIRUS-LIKE PARTICLE ANALOGUE | 2004 |
|
RU2351362C2 |
COMPOSITION FOR IMMUNE RESPONSE STIMULATION (VARIANTS), METHODS FOR PRODUCTION AND USING THEREOF AND METHOD FOR IMMUNE RESPONSE STIMULATION USING THE SAME | 2002 |
|
RU2316347C2 |
COMBINATION INCLUDING IMMUNE-STIMULATING OLIGONUCLEOTIDES | 2016 |
|
RU2766693C2 |
PNEUMOCOCCAL VACCINE AND USING IT | 2010 |
|
RU2536248C2 |
Authors
Dates
2005-01-27—Published
2000-09-25—Filed