FIELD: biology.
SUBSTANCE: invention relates to compositions containing immunostimulating RNA olygomers and uses thereof. Claimed molecules of immunostimulating RNA having chain length of 5-40 nucleotides and including at least one guanine and at least one uracyl have immunostimulating properties and represent exclusive ligands of one or more Toll-like receptors, including Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8).
EFFECT: composition and methods for stimulation of immune response activation.
120 cl, 23 ex, 20 dwg
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Authors
Dates
2007-07-20—Published
2003-04-04—Filed