METHOD FOR MANUFACTURING VACCINE AGAINST INFECTIOUS LARYNGOTRACHEITIS IN POULTRY Russian patent published in 2005 - IPC

FIELD: veterinary virology, biotechnology.

SUBSTANCE: the present innovation deals with infecting 9-11-d-aged embryos of SPF-hens with "O #112-DEP" viral strain of poultry laryngotracheitis (pcs), incubation of infected system, collection of virus-containing material, addition of protective medium to virus-containing material at the ratio of 1:19-3:17, correspondingly, drying the obtained mixture due to lyophilization followed by the control of the target product. As a result, one should obtain virus vaccine against infectious poultry laryngotracheitis at the content of virus-containing material at biological activity being, at least, 6.0 lg EID₅₀/cu. cm. The present method enables to increase immunogenic activity, safety and areactogenicity of the target product and widen the number of preparations for specific prophylaxis of infectious poultry laryngotracheitis being of high immunogenic activity, safety and areactogenicity at ocular and oral ways of immunization.

EFFECT: higher efficiency.

3 cl, 8 ex, 7 tbl