FIELD: veterinary virology, biotechnology.
SUBSTANCE: vaccine comprises an avirulent antigen material from the strain "O № 112-DEP" of homologous virus and an oily adjuvant taken in the effective ratio. The strain is deposited in collection of microorganisms VGNKI at registration name "O № 112-DEP". Virus of the strain "O № 112-DEP" is reproduced in SPF-chicken embryos (age 9-11 days) with infectious activity at least 6.0 Ig EID50/cm3. Ethyleneimine dimer in the concentration 0.1% is used as an inactivating agent. Vaccine is used for immunization of clinically health poultry of age 25-30 days in the volume 0.5 cm3 by intramuscular route. In grafted poultry the immunity occurs on 14-21 days after vaccination. Invention provides expanding assortment of inactivated emulsion vaccines against laryngotracheitis in poultry eliciting high antigen and immunogenic activity and harmless.
EFFECT: valuable properties of vaccine.
5 cl, 5 tbl
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Authors
Dates
2005-07-27—Published
2003-12-24—Filed