6-NITRO-2-IMINOCOUMARIN 3-CARBOXYLIC ACID 4-TOLUIDIDE SILVER SALT ELICITING ANTIBACTERIAL ACTIVITY Russian patent published in 2005 - IPC

Abstract RU 2247119 C1

FIELD: organic chemistry, medicine.

SUBSTANCE: invention relates to new compounds of coumarone class, namely, to 6-nitro-2-iminocoumarin 3-carboxylic acid 4-toluidide silver salt of the formula (1): that elicits an antibacterial effect and can be used in medicine. Invention provides preparing a new compound eliciting an antibacterial effect with respect to S. aureus, E. coli, and C. albicans with mononuclear cells values 0.25; 0.5 and 7.8 mcg/ml, respectively, and with acute toxicity value LD50 for these compounds 2 460 ± 230 mg/kg.

EFFECT: valuable properties of compound.

1 cl, 1 tbl, 2 ex

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RU 2 247 119 C1

Authors

Ukhov S.V.

Kon'Shin M.E.

Novikova V.V.

Odegova T.F.

Syropjatov B.Ja.

Dates

2005-02-27Published

2003-07-29Filed