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2 429 225

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IPC

C07C231/04(2006-01-01)

C07C235/32(2006-01-01)

C07C235/78(2006-01-01)

A61K31/167(2006-01-01)

A61P31/00(2006-01-01)

(21) (22)

Application

2009138209/04, 2009-10-15

(24)

Start date

2009-10-15

(22)

Actual filing date

2009-10-15

(45)

Published

2011-09-20

(72)

Inventor

Mel'Nikova Natal'Ja AleksandrovnaOdegova Tat'Jana FedorovnaBorodin Anton Jur'EvichIgidov Nazim MusabekovichChashchina Svetlana ViktorovnaBorodina Tat'Jana ViktorovnaKirillova Rimma Valentinovna

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennaja Farmatsevticheskaja Akademija Federal'Nogo Agentstva Po Zdravookhraneniju I Sotsial'Nomu Razvitiju" Vpo Pgfa Roszdrava)

N-SUBSTITUTED AMIDES OF 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL) 2-BUTENOIC ACID, EXHIBITING ANTIMICROBIAL ACTIVITY Russian patent published in 2011 - IPC C07C231/04 C07C235/32 C07C235/78 A61K31/167 A61P31/00

Abstract RU 2429225 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel biologically active substance, -N-substituted amide of 2-hydroxy-4-oxo-4-(4¹-chlorophenyl) 2-butenoic acid of formula

(I), R=2,6-(CH₃)₂C₆H₃ (Ia); 2,4,6-(CH₃)₃C₆H₂ (Ib).

EFFECT: marked antimicrobial activity and low toxicity.

1 cl, 2 ex, 1 tbl

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RU 2 429 225 C2

Authors

Mel'Nikova Natal'Ja Aleksandrovna

Odegova Tat'Jana Fedorovna

Borodin Anton Jur'Evich

Igidov Nazim Musabekovich

Chashchina Svetlana Viktorovna

Borodina Tat'Jana Viktorovna

Kirillova Rimma Valentinovna

Dates

2011-09-20—Published

2009-10-15—Filed