FIELD: chemistry.
SUBSTANCE: described is a novel way of regiospecific synthesis of 1-[di(4-cyanophenyl)methyl]-1,2,4-triazole by reacting 4-amino-1,2,4-triazole with di(4-cyanophenyl)-halogenmethane and the obtained 4-amino-1-[di(4-cyanophenyl)methyl]-1,2,4-triazolium-1 salt is quantitatively deamidated with sodium nitrite in hydrochloric acid.
EFFECT: obtaining a compound I with high output and high degree of purity without further purification.
5 cl, 2 ex
| Title | Year | Author | Number |
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RU2527473C1 |
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| 0 |
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SU520918A3 | |
| PROCESS FOR PRODUCTION OF DERIVATIVES OF TRIASOLOPYRIMIDINE OR MIXTURE THEREOF OR THEIR PHARMACEUTICALLY-ACCEPTABLE SALTS WITH METALS | 0 |
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| METHOD FOR PREPARING 5-AMINO-3-[N-ACYL-N-ALKYLAMINO]-1-PHENYL-1,2,4-TRIAZOLES AND 5-AMINO-3-[N-SULFONYL-N-ALKYLAMINO]-1-PHENYL-1,2,4-TRIAZOLES | 2004 |
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