FIELD: medicine.
SUBSTANCE: method involves determining CYP2C19 gene polymorphism. Homozygotes wt/wt being available in both alleles of the gene, radical surgical treatment is selected as duodenal cicatricial ulceration lesion removal with vagotomy, stomach resection or their combination. Mutations being available in both CYP2C19 gene alleles (mutant phenotype), drug therapy or its combination with isolated organ-saving operations on duodenum is selected.
EFFECT: high accuracy in selecting appropriate treatment method; accelerated treatment course; reduced recurrence number.
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Authors
Dates
2005-05-27—Published
2003-12-05—Filed