SURGICAL METHOD FOR APPLYING PHOTODYNAMIC TREATMENT TO SUBRETINAL NEOVASCULAR MEMBRANES Russian patent published in 2005 - IPC

FIELD: medicine.

SUBSTANCE: method involves applying vitrectomy, retinotomy and mechanical removal of subretinal neovascular membranes from under the retina. 0.1-2% photosensibilizer agent solution of clorine row selected from a group containing photolon, radachlorine, or photoditazine at a dose of 0.8-1.1 mg/kg is intravenously introduced. Visual control of subretinal neovascular membrane cells fluorescence is carried out with photodynamic fluorescent diagnosis method being applied. Trans-scleral laser radiation with wavelength of 661-666 nm during 40-140 s with radiation dose being equal to 30-130 J/cm². Irradiation is carried out via laser light guide having lens mounted in advance in tunnel formed in inferoexterior or superoexterior quadrant at the subretinal neovascular membrane localization place. The light guide is removed after having finished photodynamic therapy course. Surgical removal of the subretinal neovascular membrane is carried out in 2-3 weeks concurrently with subretinal edema and hemorrhages resorption taking place with following perfluororganic compound tamponade that is substituted with silicon oil in course of operation. The operation is finished with sutures placed over sclerectomy and conjunctiva areas.

EFFECT: enhanced effectiveness of treatment; avoided hemorrhages occurrence.

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