METHOD FOR PREPARING PURIFIED HEMATIN COMPLEX IRON-SACCHARIDE AND PREPARED PRODUCT Russian patent published in 2005 - IPC

FIELD: medicine, pharmacology.

SUBSTANCE: invention relates to a method for preparing and purifying active hematin particles presenting in complexes hematin - saccharide and comprising complex of ferrous (III) - sodium gluconate in sucrose, complex ferrous (III) oxide hydrate - sucrose and complex ferrous (III) - saccharate. Method is developed on basis for separation of complex iron - saccharide from one or some filling agents and, preferably, by lyophilization. Isolation of complex iron - saccharide provides carrying out its analytical quantitative determination, additional concentrating or purifying as new useful product, preparing reconstructed preparations for new and useful medicinal agents. Capacity to isolating complex iron - saccharide responsible for hematin fraction including its lyophilized form is provided also by agents for preparing analytical material designated for control and proving the pharmacological unity, safety for patient and clinical indices of hematin complexes. Invention provides carrying out the analytical monitoring, standardization and control of quality during processes for producing hematin and for standardization in their using.

EFFECT: improved preparing method, valuable properties of end product.

45 cl, 2 tbl, 10 dwg, 11 ex