FIELD: medicinal pharmacology.
SUBSTANCE: the present innovation deals with minor peptides which could be characterized with the following formula: X-A-B-C-Y-NH2, where X - α-aminoisobutiryl, tranexamyl (i.e.4-(aminomethyl)cyclo-hexane carbonyl), isonipecotinyl, γ-aminobutiryl, hydrogen or imidazolylacetyl, A - D-2-methyltryptophan, D-β-(2-naphthyl)alanine or D-tryptophan, B - D-2-methyltryptophan, D-β-(2-naphthyl)alanine, D-tryptophan or is absent, C - D-2-methyltryptophan, phenylalanine or is absent, Y - lysine or arginine, where D means dextroisomer, or pharmaceutically acceptable salt of peptide that induces penile erection. Also, pharmaceutical composition is suggested that contains these peptides, and methods for treating erectile dysfunctions.
EFFECT: higher efficiency.
12 cl, 7 ex
Authors
Dates
2005-11-27—Published
2000-11-04—Filed