POLYPEPTIDE COMPOUNDS CONTAINING D-2-ALKYLTRYPTOPHAN THAT STIMULATES GROWTH HORMONE RELEASE Russian patent published in 2000 - IPC

Abstract RU 2157378 C2

FIELD: chemistry of peptides. SUBSTANCE: invention describes the novel peptide of the formula (I): AD-Mrp-(Al)n-B-C where AD is Thr-His, imidazole-acetyl, isonipetotyl, 4-aminobutyryl and D is dextroisomer; Mrp means 2-(C1-C3-alkyl)-tryptophan; n = 0 or 1; BD is Trp; D is β-Nal; C is NH2, Phe-Lys-NH2 and additive salts of pharmaceutically acceptable organic or inorganic acids. Peptide has amino acid D-2-alkyltryptophan that is able to release somatotrophic growth hormone. EFFECT: valuable hormonal properties of polypeptide. 9 cl, 1 tbl, 2 ex

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RU 2 157 378 C2

Authors

Romano Degengi

Dates

2000-10-10Published

1995-09-13Filed