CULTIVATION OF BACTERIUM LAWSONIA INTRACELLULARIS, STRAINS L. INTRACELLULARIS, CULTIVATION OF BACTERIUM L. INTRACELLULARIS (VARIANT), METHOD FOR PRODUCTION OF ATTENUATED STRAIN L. INTRACELLULARIS, METHOD FOR ANTIBODY DETECTION, VACCINE, METHOD FOR INDUCING OF IMMUNE RESPONSE AND ATTENUATED STRAIN L. INTRACELLULARIS N343NP40WK Russian patent published in 2005 - IPC

Abstract RU 2265849 C2

FIELD: biotechnology, in particular production of vaccines and diagnosis objects.

SUBSTANCE: bacterium Lawsonia intracellularis is cultivated in Hep-2, Me Coys or IEC-18 cells in suspension at oxygen concentration from more than 0 to about 18 %. Vaccines, containing bacterium L. intracellularis obtained by claimed method, is useful in inducing of immune response to said bacteria in animals.

EFFECT: improved method for large-scale cultivation of bacterium L. intracellularis.

21 cl, 5 tbl, 6 ex

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RU 2 265 849 C2

Authors

Knittel Dzheffri P.

Ruf Majkl B.

Dates

2005-12-10—Published

1996-06-05—Filed