FIELD: medicine.
SUBSTANCE: method involves increasing receptor activity, that is activated with proliferating agent of peroxis, by introducing NADP+-dependent isocitrate dehydrogenase (IDPc), IDPc gene or NADPH, selecting antisense molecule inhibiting fat deposit or nitroglycerides and cholesterol production using IDPc gene, and treating metabolism disorder diseases like adiposity, hyperlipiemia or hepatic fat infiltration by introducing antisense molecule of IDPc gene or IDPc gene inhibitor like oxalomalic acid or methyl isocitric acid.
EFFECT: enhanced effectiveness of treatment; reduced NADP level in cells.
5 cl, 10 dwg
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