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(19)

RU

(11)

2 585 491

(13)

C2

(51)

IPC

C12N15/113(2010-01-01)

A61K31/713(2006-01-01)

A61K31/7052(2006-01-01)

A61P3/04(2006-01-01)

A61P3/00(2006-01-01)

(21) (22)

Application

2013100002/10, 2011-06-06

(24)

Start date

2011-06-06

(22)

Actual filing date

2011-06-06

(45)

Published

2016-05-27

(72)

Inventor

Olson Eric N.Carrer Michele

(73)

Holder

Board Of Regents, The University Of Texas System

REGULATION OF METABOLISM USING MIR-378 Russian patent published in 2016 - IPC C12N15/113 A61K31/713 A61K31/7052 A61P3/04 A61P3/00 

Abstract RU 2585491 C2

FIELD: biotechnologies.

SUBSTANCE: invention relates to biotechnology, specifically to method of treating metabolic disorder in individual by introducing agents, which modulate activity and microRNA expression, and can be used in medicine. Present invention provides method of treating disorders, such as obesity, diabetes or metabolic syndrome, in individual by adding inhibitor expression or activity of miR-378 and/or miR-378*.

EFFECT: invention enables effective therapy of wide range of metabolic disorders caused by violation of signal transmission using leptin.

9 cl, 19 dwg, 6 ex

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RU 2 585 491 C2

Authors

Olson Eric N.

Carrer Michele

Dates

2016-05-27—Published

2011-06-06—Filed

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