FIELD: medicine, endocrinology. SUBSTANCE: the method deals with injecting an antagonist of retinoid-X-receptor separately or in combination with peroxys-proliferative-activating receptor (PPARgamma). Thiazolidine dion derivatives could be referred to the latter. For this purpose it is, also, recommended to use pharmaceutical compositions containing the mentioned components. The method provides to increase glucose intake by tissues due to decreasing the content of glucose, triglycerides, cholesterol in blood. EFFECT: higher efficiency of therapy. 31 cl, 8 dwg, 2 tbl
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