FIELD: organic chemistry, antibiotics, pharmacy.
SUBSTANCE: invention describes crystalline forms A, C and D of erythromycin derivative of the formula (VII): 
. Crystalline forms are prepared by recrystallization of crude fumarate crystal from an alcoholic solvent (form A) and, additionally, from ethyl acetate (form C) or, additionally, from an aqueous ethyl acetate (form D). Also, invention relates to methods for preparing intermediate compounds. Prepared crystalline forms possess the better quality, in particular, high stability that is important in preparing pharmaceutical preparations.
EFFECT: improved preparing methods.
16 cl, 8 dwg, 13 ex
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