FIELD: chemistry.
SUBSTANCE: present invention relates to a method of producing 1-(3,4-dichlorobenzyl)-5-octyl biguanide of formula
or salt thereof, involving reaction of 1-cyano-3-octylguanidine or salt thereof with 3,4-dichlorobenzylamine or salt thereof in an organic ester solvent.
EFFECT: obtaining the desired product with high output using a safe and simple method.
7 cl, 12 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PIPERAZINYL PYRIMIDINE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | 2013 |
|
RU2608315C2 |
| ESTER DERIVATIVE OF 2-AMINO-BICYCLO[3,1,0]HEXANE-2,6-DICARBOXYLIC ACID | 2004 |
|
RU2409557C2 |
| PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATING PSYCHIATRIC DISORDERS | 2006 |
|
RU2402549C2 |
| METHOD FOR PREPARING BENZYLAMINE | 2000 |
|
RU2227141C2 |
| METHOD OF PRODUCING THIAZOLE DERIVATIVE | 2006 |
|
RU2397161C2 |
| CONDENSED THIENOPYRIMIDINES INHIBITING ACTIVITY OF PHOSPHODIESTERASE V, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION | 1999 |
|
RU2224760C2 |
| METHODS FOR PREPARING BENZOXAZINE DERIVATIVE, METHODS FOR PREPARING ITS INTERMEDIATE COMPOUND AND INTERMEDIATE COMPOUNDS | 2000 |
|
RU2258069C2 |
| METHOD OF OBTAINING CARBOSTYRENE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS WITH ACIDS | 0 |
|
SU1140687A3 |
| CRYSTALLINE FORMS OF 3-(2,4-DICHLOROBENZYL)-2-METHYL-N- (PENTYLSULFONYL)-3H-BENZIMIDAZOLE-5-CARBOXAMIDE | 1999 |
|
RU2228931C2 |
| METHOD OF SYNTHESIS OF CRYSTALLINE 7-[2-(2- AMINOTHIAZOLE-4-YL) -2-(Z)-METHOXYIMINOACETAMIDO]-3- [(-1-METHYL-1- PYRROLIDINIO) -METHYL]- CEPH-3-EM -4-CARBOXYLATE MONO- OR DIHYDRATE DIHYDROCHLORIDE ESSENTIALLY FREE FROM ANTIISOMER AND Δ-ISOMER | 1992 |
|
RU2042681C1 |
