FIELD: organic chemistry, microbiology, pharmacy.
SUBSTANCE: invention relates to new biologically active compounds. Invention describes a compound of the formula (1):
wherein R1 means carbon chain with 2-30 carbon atoms that can be linear, branched, saturated and can be substituted once or twice with the following groups: -OH, =O, -(C1-C6)-alkyl or the group:
; R2 means (C1-C6)-alkyl; E means phosphorus atom (P); each X1, X2 and X3 means independently of one another -O- in its all stereochemical forms and mixtures of these forms taken in any ratio, and its physiologically acceptable salts also. Also, invention describes a method for preparing cyclipostins and the strain Streptomyces HAG 004107, DSM 13381 as a producer of cyclipostins. Invention provides preparing new compounds possessing valuable biological properties.
EFFECT: improved preparing method, valuable properties of substances.
12 cl, 9 tbl, 21 ex
Title | Year | Author | Number |
---|---|---|---|
PLURAFLAVINES, METHODS FOR THEIR PREPARING AND COMPOSITION BASED ON THEREOF | 2001 |
|
RU2255940C2 |
DERIVATIVES OF CALOPOROSIDE, METHOD FOR THEIR PREPARING AND THEIR USING | 2002 |
|
RU2282634C2 |
PEPTIDES WITH LARGE NUMBER OF BRIDGE LINKS, WHICH ARE EXTRACTED FROM ACTINOMADURA NAMIBIENSIS | 2009 |
|
RU2498995C2 |
PERCIQUINNINE, METHOD FOR ITS PREPARING AND ITS USING AS PHARMACEUTICAL AGENT | 2001 |
|
RU2266290C2 |
PHOSPHORYLATED DERIVATIVES OF PHENYLACETIC ACID, MEDICINAL AGENT FOR TREATMENT OF ALLERGIC DISEASE | 1998 |
|
RU2202556C2 |
COMPOUND WK-5344A AND COMPOUND WK- 5344B, METHOD FOR THEIR OBTAINING AND THEIR PRODUCING STRAIN OF STREPTOMYCES SP | 1999 |
|
RU2201964C2 |
PYRANONE DERIVATIVE, METHOD OF ITS PREPARING AND PHARMACEUTICAL COMPOSITION | 1994 |
|
RU2098422C1 |
MUMBAISTATIN, METHOD FOR ITS PREPARING AND ITS APPLICATION AS PHARMACEUTICAL PREPARATION | 1999 |
|
RU2221870C2 |
COMPLEX FORMING COMPOUNDS | 2012 |
|
RU2619939C2 |
INDOLE AND BENZOXAZINE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | 2009 |
|
RU2512283C2 |
Authors
Dates
2005-12-27—Published
2001-04-25—Filed