CYCLIPOSTINS, METHOD FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, METHOD FOR ITS PREPARING AND STRAIN STREPTOMYCES AS PRODUCER OF CYCLIPOSTINS Russian patent published in 2005 - IPC

Abstract RU 2266911 C2

FIELD: organic chemistry, microbiology, pharmacy.

SUBSTANCE: invention relates to new biologically active compounds. Invention describes a compound of the formula (1):

wherein R1 means carbon chain with 2-30 carbon atoms that can be linear, branched, saturated and can be substituted once or twice with the following groups: -OH, =O, -(C1-C6)-alkyl or the group:

; R2 means (C1-C6)-alkyl; E means phosphorus atom (P); each X1, X2 and X3 means independently of one another -O- in its all stereochemical forms and mixtures of these forms taken in any ratio, and its physiologically acceptable salts also. Also, invention describes a method for preparing cyclipostins and the strain Streptomyces HAG 004107, DSM 13381 as a producer of cyclipostins. Invention provides preparing new compounds possessing valuable biological properties.

EFFECT: improved preparing method, valuable properties of substances.

12 cl, 9 tbl, 21 ex

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RU 2 266 911 C2

Authors

Verteshi Laslo

Ehrlikh Klaus

Kurts Mikhel'

Vink Joakhim

Dates

2005-12-27Published

2001-04-25Filed