METHOD FOR PREVENTING THE DEVELOPMENT OF NONTHROMBOGENIC COMPLICATIONS IN POSTOPERATIONAL PERIOD Russian patent published in 2006 - IPC A61K31/205 A61P43/00 

Abstract RU 2268039 C2

FIELD: medicine, surgery.

SUBSTANCE: one should study functional state of hemostasis system based upon electro- and biochemical coagulogram, and at availability of a friable clot: the value of minimal amplitude of electrocoagulogram being above 0.6 c.u. - it is necessary to introduce dicynon per 250 mg intravenously 4 times daily and additionally in case of hypothrombinemia one should carry out infusion of freshly frozen plasma intravenously at the dosage of 3-6 ml/kg patient's body weight, and at availability of hyperactivation of fibrinolysis one should introduce inhibitors of proteases: at first intravenously by bolus technique, and then - as intravenous continuous infusion; moreover, in case of medicinal correction of hemostasis system with anticoagulants in case of hypothrombinemia their dosages should be decreased till achieving normocoagulation. The present innovation enables to restore body hemostasis system due to individually matched therapeutic tactics that, in its turn, enables to prevent postoperational complications.

EFFECT: higher efficiency and accuracy of prophylaxis.

1 cl, 1 dwg, 3 ex, 1 tbl

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RU 2 268 039 C2

Authors

Zabolotskikh Igor' Borisovich

Sin'Kov Sergej Vasil'Evich

Manujlov Aleksandr Mikhajlovich

Shaposhnikov Sergej Aleksandrovich

Dates

2006-01-20Published

2003-12-18Filed