FIELD: medicine, oncology.
SUBSTANCE: in plasma of peripheral blood in children one should detect cathepsin D activity and antiproteolytic activity and calculate coefficient of their ratio. At obtaining the value of coefficient being equal 10.5 ± 2 one should detect lymphadenopathy of benign genesis in a child to choose a waiting-type tactics at prescribing antiphlogistic therapy. At coefficient value ranged 30-100 on should detect malignant lymphoproliferative process in a child to immediately fulfill an excision biopsy of a lymph node along histological studying and at proving the diagnosis special therapy should be indicated. Application of the present method enables to conduct additional objective differential-diagnostic test under disputable cases at the stage being before carrying out histological analysis of lymph nodes and prescribe necessary therapy for every concrete case in due time.
EFFECT: higher accuracy of differential diagnostics.
3 ex, 1 tbl
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Authors
Dates
2006-01-20—Published
2004-05-12—Filed