WAY OF TREATMENT OF REFRACTORY FORMS OF LYMPHOGRANULOMATOSIS Russian patent published in 2009 - IPC A61K35/28 A61K31/704 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely to oncology, and can be used for treatment of patients with resistant lymphogranulomatosis forms. The essence of the invention consists that a medullar suspension taken of an ileal bone of the patient is centrifugated during 30 minutes at 1500 rpm. Then the plasma is selected, divided on two parts and frozen at -40°C, corpuscles of a medullar suspension are dilluted with a sterile normal saline solution, incubated with the chemopreparations in a thermostat at 37°C during 30 minutes and reinfused to the patient intravenously driply. Further in 14 and 28 days a la carte the plasma of a medullar suspension is defrozen, diluted with a sterile normal saline solution. Every portion is incubated with the same chemopreparations in the same doses in a thermostat at temperature of 37°C during 30 minutes and reinfused to the patient intravenously driply. All complex of medical procedures is repeated in 2 weeks.

EFFECT: possibility to reach remission at patients at the expense of rising of antitumoral activityof chemopreparations at their incubation with cells of a medullar suspension and nonspecific stimulation of immunity by antigens of plasma processed with chemopreparations of a medullar suspension.

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