METHOD FOR CARRYING OUT PHOTODYNAMIC DERMABRASION Russian patent published in 2006 - IPC A61N5/67 

FIELD: medicine.

SUBSTANCE: method involves degreasing pathologically transformed area with preparation containing no alcohol. Scanning pulsating laser radiation having wavelength of 800-930 nm and frequency of 140-160 Hz is applied for 5-20 min under radiation power of 4-10 W in pulse and its duration being equal to 50-300 Ns. Then, photosensitizing cream, gel or ointment containing chlorine row photosensitizer is applied. The photosensitizer is selected from a group containing Photolon, Radachlorine or Photodithazine in the amount of 0.1 to 2% or porphyrin row photosensitizer selected from a group containing Photogem or Photofrin in the amount of 0.1 to 1%. After having exposed pathologically transformed skin area away from light during 30-180 min, remaining photosensitizer residue is removed without injuring epidermis. The pathologically transformed skin area is insulated from intact skin with material impermeable for laser radiation. Its laser radiation is carried out with parallel light beam passed through square, triangular, rectangular, pentagonal or hexagonal shape stencil moving it edge-to-edge over the whole pathologically transformed skin area. Wavelength is equal to 661-666 nm when using chlorine row photosensitizer or 630-633 nm when using porphyrin row photosensitizer. Radiation power density is equal to 30-60 J/cm². Not more than 100 cm² of pathologically transformed skin area is treated in one photodynamic therapy session. Dermabrasion of the next pathologically transformed skin area is carried out after healing the preceding one.

EFFECT: accelerated epithelialization period; reduced risk of infectious complications; predictable cosmetic results.

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