FIELD: organic chemistry, medicine, gastroenterology, oncology.
SUBSTANCE: invention relates to a new agent used in treatment of gastroenteric tumors. Invention describes an agent for treatment of gastroenteric tumors representing compounds of the general formula: A-X1-NO2 or their salts wherein A means -RCO(X)t wherein t represents a whole number from 0 to 1; X means oxygen atom (O); R is taken among the following groups: (IA), (IIA), (IIIA), (IVA), (VA) and (VIA) such as given in the invention claim; X1 in the formula A-X1-NO2 means a bivalent binding bridge taken among the following: -YO- wherein Y means a liner or when possible a branched (C1-C20)-alkylene comprising preferably from 2 to 5 carbon atoms, or possibly a substituted cycloalkylene comprising from 5 to 7 carbon atoms of the formula: wherein n3 means a whole number from 0 to 3; wherein nf means a whole number from 1 to 6 but preferably from 2 to 4; wherein R1f means hydrogen atom (H), -CH3; nf means a whole number from 1 to 6 but preferably from 2 to 4. Invention provides a new medicinal agent used in treatment of gastroenteric tumors.
EFFECT: valuable medicinal properties of agent.
2 cl, 11 tbl, 18 ex
Authors
Dates
2006-02-10—Published
1997-09-02—Filed