METHOD FOR ENHANCING OF CYCLOPHOSPHAN ANTITUMOR AND ANTIMETASTATIC ACTIVITY IN EXPERIMENT Russian patent published in 2006 - IPC A61K31/675 A61K35/48 A61P35/00 G09B23/28 

Abstract RU 2270682 C2

FIELD: experimental medicine and oncology.

SUBSTANCE: claimed method includes intraperitoneum cyclophosphan administration in dose of 120 mg/kg and intravenous transplantation of fetal liver steam cells to experimental animal. Fetal liver steam cells are transplanted for 3 days before cyclophosphan administration in dose of 25x106 cells/kg of mass.

EFFECT: decreased tumor growth, reduced frequency and area of metastasis due to optimization of cyclophosphan and steam cells administration.

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RU 2 270 682 C2

Authors

Kokorev Oleg Viktorovich

Cherdyntseva Nadezhda Viktorovna

Zjuzikova Olesja Vladimirovna

Dates

2006-02-27Published

2004-03-09Filed