FIELD: medicine.
SUBSTANCE: invention refers to 3-oxo-28-(N-methylpiperazine)-carbonyl-lup-20(29)-ene of formula (I) which can be used in medicine as a corrective agent for paraneoplastic damages and toxic effects of cytostatic polychemotherapy. 
.
EFFECT: compound I shows an apparent anticancer activity, reduces severity of pathological changes in tissues caused by paraneoplastic syndromes; in cytostatic polychemotherapy, it exhibits an apparent antioxidant and cytoprotective effect in normal cells of viscera and thereby does not stimulate proliferation and dissemination of a tumour.
8 ex, 8 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| N-[3-OXO-LUPANO-28-YL]-PIPERIDINE - AGENT HAVING ANTI-TUMOUR, ANTI-METASTATIC, ANTI-INFLAMMATORY AND CYTOPROTECTIVE ACTIVITY | 2011 |
|
RU2466136C1 |
| N-[3-OXO-LUPANO-28-YL]-MORPHOLINE - AGENT FOR CORRECTION OF CYTOTOXIC LIVER DAMAGES WITH ANTITUMOUR AND ANTIMETASTATIC ACTIVITY | 2011 |
|
RU2461563C1 |
| CORRECTOR OF CYTOSTATIC POLYCHEMOTHERAPY | 2007 |
|
RU2353623C1 |
| AGENT FOR CORRECTING CYTOTOXIC EFFECTS OF PARANEOPLASTIC PROCESSES AND CHEMOTHERAPY SHOWING ANTICANCER ACTIVITY | 2011 |
|
RU2447888C1 |
| AGENT FOR CORRECTION OF CYTOSTATIC POLYCHEMOTHERAPY WITH ANTI-INFLAMMATORY ACTIVITY | 2010 |
|
RU2425680C1 |
| ANTI-INFLAMMATORY MEDICATION WITH ANTICOAGULANT, ANTITUMOUR AND ANTIMETASTETIC ACTIVITY | 2009 |
|
RU2412712C1 |
| METHOD FOR ENHANCING OF CYCLOPHOSPHAN ANTITUMOR AND ANTIMETASTATIC ACTIVITY IN EXPERIMENT | 2004 |
|
RU2270682C2 |
| AGENTS IMPROVING ANTICANCER AND ANTIMETASTATIC ACTIVITY OF CYTOSTATICS | 2011 |
|
RU2471496C1 |
| METHOD FOR CREATING BIOLOGICAL MODEL OF MODERATE GROWTH INHIBITION OF TUMOUR AND METASTASES IN LEWIS LUNG CARCINOMA WITH PROLONGED CYCLOPHOSPHANINE-INDUCED LEUKOPENIA IN MICE | 2012 |
|
RU2488173C1 |
| AGENT INCREASING ANTI-METASTATIC ACTIVITY OF CYCLOPHOSPHAN | 2016 |
|
RU2613189C1 |
