METHOD FOR PREDICTING ARTERIAL HYPERTENSION Russian patent published in 2006 - IPC A61B5/02 

FIELD: medicine, therapy, cardiology.

SUBSTANCE: one should carry out daily monitoring of arterial pressure (DMAP) due to transportable monitors based upon auscultative and/or oscillometric methods for detecting arterial pressure through preset intervals. Either due to manual or automatically controlled techniques it is necessary to calculate Kerdo's index for i- measurement of arterial pressure and/or during carrying out daily monitoring of arterial pressure, and/or day-time hours of daily monitoring of arterial pressure evaluated during the period of its fulfillment , and/or nocturnal hours of daily monitoring of arterial pressure estimated by the following formulas: where KI_i - the value of Kerdo's index for i-measurement of arterial pressure; DAP_i - the value of diastolic arterial pressure for i-measurement of the latter; HR_i - the value of HR for i-measurement of diastolic arterial pressure, KI(T) - the value of Kerdo's index calculated as average arithmetic value for the period of performing daily monitoring of arterial pressure, T - time for carrying out daily monitoring of arterial pressure, N - total number of alterations in arterial pressure while carrying out daily monitoring of the latter, KI(D) - the value of Kerdo's index calculated as average arithmetic value for day-time hours during carrying out daily monitoring of arterial pressure, KI(N) - the value of Kerdo's index calculated as average arithmetic value for nocturnal hours during carrying out daily monitoring of arterial pressure, moreover, variants for KI values for i-measurement of arterial pressure KI_i, KI(D) and KI(N) should be distributed into three gradations: KI=0, KI<0 and KI>0. In case of KI=0 one should observe complete autonomic balance (eutonia), at KI<0 one should state upon the predominance of parasympathetic impacts (vagotonia), At KI of the most negative value it is possible to observe the increase of parasympathetic impact (hypervagotonia). At KI>0 one should conclude upon the predominance of sympathetic impacts (sympathicotonia). At KI of the most positive value it is possible to observe increased influence of sympathetic tonicity (hypersympathicotonia). In healthy people at the state of rest during day-time period one should note sympathetic activity (sympathicotonia) in men and parasympathetic impact (vagotonia) in women, and at development of arterial hypertension and its stabilization one should register increased parasympathetic tonicity in men (vagotonia) and decreased parasympathetic and increased sympathetic background impacts in women (sympathicotonia). Hypersympathicotonia in men and hypervagotonia in women in case of arterial hypertension illustrates unfavorable disease prediction, especially in young patients, or depicts diagnostics of symptomatic arterial hypertension. Moreover, in healthy persons at nocturnal period one should observe parasympathetic autonomic tonicity (vagotonia), and in case of progressing disease flow at unfavorable prediction and disorders in autonomic regulation at the level of suprasegmentary autonomic apparatuses in patients with arterial hypertension one should state upon sympathetic autonomic tonicity (sympathicotonia). The innovation suggested enables to increase the accuracy in evaluating the character of arterial hypertension flow.

EFFECT: higher accuracy and efficiency of diagnostics.

1 cl, 2 ex, 11 tbl