4,4'-SULFONYL-BIS-(N,N'-DIMETHYLAMMONIOMETHYLENEANILINE)-CHLORIDE, 6-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-SULFONATE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2006 - IPC C07C317/32 C07D239/60 A61K31/505 A61P31/08

Abstract RU 2275356 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to 4,4'-sulfonyl-bis-(N,N'-dimethylammoniomethyleneaniline)-chloride, 6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonate of the formula (I) eliciting antibacterial, antimycobacterial and immunotropic activities. Also, invention describes a pharmaceutical composition based on compound of the formula (I).

EFFECT: valuable medicinal properties of compounds and composition.

3 cl, 7 tbl, 2 ex

Similar patents RU2275356C2

Title	Year	Author	Number
IMMUNOTROPIC N, N '-(SULPHONYLDI-1,4-PHENYLENE)BIS[(N",N'"-DIMETHYL)METHYLIMINOMETHANE]1,2,3,4-TETRAHYDRO-6-METHYL-2,4-DIOXO-5-PYRIMIDINESULPHONATE	2007	Khaitov Musa Rakhimovich Tsyvkina Galina Ivanovna Sedova Svetlana Nikolaevna Gomzhin Andrej Mikhajlovich Savel'Ev Evgenij Aleksandrovich Khimich Galina Nikolaevna Khimich Nikolaj Nikolaevich	RU2357960C1
N,N'-(SULFONYLDI-1,4-PHENYLENE)-BIS-(N'',N''-DIMETHYLFORM- -AMIDINE)-1,2,3,4-TETRAHYDRO-6-METHYL-2,4-DIOXO-5-PYRIMIDINE SULFONATE STIMULATING CELLULAR METABOLISM AND SHOWING IMMUNOTROPIC AND ANTIBACTERIAL ACTIVITY	1997	Goloshchapov N.M. Michurina E.A. Filipskikh T.P. Goloshchapova E.N. Kostjuk L.E. Sudareva T.T. Khaitov R.M. Tsyvkina G.I. Reshetov A.L.	RU2136668C1
N-(6-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5H-PYRIMIDINESULFONE)-N′- ISONICOTINOYL HYDRAZIDE DISODIUM SALT ELICITING ANTIBACTERIAL AND IMMUNOTROPIC ACTIVITY AND MEDICINAL AGENT BASED ON THEREOF	1999	Goloshchapov N.M. Filipskikh T.P. Kostjuk L.E. Goloshchapova E.N. Michurina E.A. Reshetov A.L. Zavarzin A.A.	RU2191015C2
N-(6-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINYL-5-SULFONYL)PYRAZINE- -2-CARBOXAMIDE POSSESSING ANTI LEPROTIC AND ANTITUBERCULOSIS AND IMMUNOTROPIC ACTIVITY, METHOD FOR THEIR PRODUCTION	1996	Goloshchapov N.M. Sudareva T.T. Kostjuk L.E. Filipskikh T.P. Goloshchapova E.N. Zaika G.F. Kuznetsov V.A.	RU2102390C1
IMMUNOMODULATING AGENT "IZOFON" SHOWING ANTIMYCOBACTERIAL ACTIVITY, METHOD OF ITS PREPARING AND USING	1997	Goloshchapov N.M. Goloshchapova E.N. Filipskikh T.P. Michurina E.A. Kostjuk L.E. Khaitov R.M. Tsyvkina G.I. Grishin V.K. Stukalov N.A. Reshetov A.L.	RU2141322C1
6-ALKYL-5-(2-ISONICOTINOYLSULFOHYDRAZOYL)URACIL HYDROCHLORIDE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF	2003	Reshetov A.L. Vereshchagina I.A.	RU2264396C2
OROTATE OF N, П,П'-DIAMINODIPHENYL SULFONE HAVING ANTILEPROSOUS AND IMMUNOTROPIC ACTIVITY	1995	Goloshchapov N.M. Filipskikh T.P. Sudareva T.T. Kostjuk L.E. Goloshchapova E.N. Khromova E.B. Zaika G.F. Merzljakova I.N. Semenova S.V. Pokrovskaja V.A.	RU2074856C1
ISONICOTINIC ACID HYDRAZIDE OROTATE HAVING ANTIBACTERIAL AND IMMUNOTROPIC ACTIVITIES	1990	Goloshchapov N.M. Sudareva T.T. Kostjuk L.E. Filipskikh T.P. Goloshchapova E.N. Ershov A.P. Zaika G.F. Pokrovskaja V.A. Semenova S.V. Merzljakova I.N.	RU2044728C1
BIS- [2,4- DIOXO-6- METHYL -1,2,3,4- TETRAHYDROPYRIMIDINE -3- (5-MET- HYL-3-THIAHEXYL) -S] -CIS- DICHLOROPLATINUM SHOWING IMMUNOTROPIC ACTIVITY	1991	Tolstikov G.A. Murinov Ju.I. Krivonogov V.P. Afzaletdinova N.G. Khisamutdinov R.A. Zarudij F.S. Lazareva D.N. Ismagilova A.F. Volkova S.S.	RU2035467C1
METHOD FOR PREPARING N-(6-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINSULFON)-N'-ISONICOTINO YL HYDRAZIDE	2003	Artemov V.A. Valeshnij S.I. Il'In V.P. Kolganov E.V. Kostjuk L.E. Lajshev V.Z. Makarov V.V. Mikhajlov V.V. Michurina E.A. Smirnov S.P.	RU2235723C1

RU 2 275 356 C2

Authors

Dmitriev Aleksandr Ivanovich

Dates

2006-04-27—Published

2004-01-12—Filed