PIPERIDINE DERIVATIVES AND AGENT COMPRISING PIPERIDINE DERIVATIVE AS ACTIVE COMPONENT Russian patent published in 2006 - IPC C07D211/22 C07D211/64 A61K31/451 A61P29/00 A61P11/06

Abstract RU 2275359 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to new derivatives of piperidine of the general formula (I): or their nontoxic salts wherein R¹ represents hydrogen atom, cyano-group; each R² and R³ represents (C₁-C₈)-alkyl, (C₃-C₇)-cycloalkyl and others; each R⁴ and R⁵ represents hydrogen atom, (C₁-C₈)-alkyl and others; R⁶ represents hydroxyl group, (C₁-C₈)-alkoxy-group and others; m represents 0 or a whole number 1-4. Compounds of the formula (I) possess inhibitory activity with respect to PDE4 and can be used in medicine in treatment of inflammatory, diabetic, allergic and other diseases.

EFFECT: valuable medicinal properties of compounds.

10 cl, 11 tbl, 111 ex

Similar patents RU2275359C2

Title	Year	Author	Number
PIPERIDINE DERIVATIVE, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION BASED ON THE SAME	2003	Otiaj Khirosi Nisita Jositaka Okhtani Tazumi Khamano Masaja	RU2308450C2
DERIVATIVES OF CARBOXYLIC ACIDS AND PHARMACEUTICAL AGENT COMPRISING THEIR AS ACTIVE COMPONENT	2002	Tani Kosuke Asada Masaki Kobajasi Kaoru Narita Masami Ogava Mikio	RU2315746C2
NOVEL PIPERIDINE DERIVATIVES	2006	Isikava Sikho Sato Nagaaki Nagase Tsujosi Tokita Sigeru Vada Tosikhiro Takakhasi Khidekazu	RU2417985C2
DERIVATIVE OF CARBOXYLIC ACID, PHARMACEUTICAL COMPOSITION AND MEDICINE OF PREVENTING AND/OR CURING DISEASES, CAUSED BY ACTIVATION OF DP RECEPTOR, USE OF SUCH DERIVATIVE FOR MAKING SUCH MEDICINE, METHOD OF PREVENTING AND/OR CURING DISEASES, CAUSED BY ACTIVATION OF DP RECEPTORS	2003	Ivakhasi Maki Kobajasi Kaoru Nambu Fumio	RU2329256C2
DERIVATIVE COMPOUNDS OF CARBOXYLIC ACID AND AGENTS COMPRISING THEREOF AS ACTIVE COMPONENTS	2002	Tadzima Khisao Nakajama Esisuke	RU2296760C2
PIPERIDINE DERIVATIVE	2008	Khigasiura Kunikhiko Ogino Takasi Ito Taidzo Ivatsuki Khirojuki	RU2475485C2
8-AZAPROSTAGLANDINE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND AGENT FOR PROPHYLAXIS OF DISEASES	2003	Tani Kousuke Kobajasi Kaoru Marujama Toru Kambe Tokhru Ogava Mikio Siroja Tsutomu	RU2306309C2
DERIVATIVES OF INDOLINE-2-ONE AND INTERMEDIATE COMPOUNDS FOR THEIR SYNTHESIS	1994	Toru Esaki Takasi Emura Ejiti Khosino	RU2128170C1
OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION	2006	Okada Minoru Kato Masaja Sato Norifumi Uno Tetsujuki Kitagaki Khideki Kharuta Dzunpej Khijama Khidetaka Sibata Tomonori	RU2418793C2
DIHYDRONAPHTHALENE DERIVATIVES AND MEDICINAL AGENT COMPRISING INDICATED DERIVATIVES AS ACTIVE COMPONENT	2001	Tadzima Khisao Nakajama Josisuke Fukusima Dajkiti	RU2268262C2

RU 2 275 359 C2

Authors

Nakai Khisao

Kisikava Katsuja

Dates

2006-04-27—Published

2001-08-09—Filed