FIELD: biotechnology, biochemistry.
SUBSTANCE: invention relates to a method for enzymatic synthesis of L-phosphinotricine by transamination reaction from 4-(hydroxymethylphosphinyl)-2-oxobutyric acid and using aspartic acid as a donor of amino-group. The quantitative conversion can be carried out by using suitable technology and equimolar amounts of donor and amino-group acceptors that results to the complete utilization of donor amino acid, i. e. aspartic acid. Using thermostable aspartate aminotransferases provides high rate of reaction and high volume output, respectively.
EFFECT: improved preparing method.
9 cl, 3 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF STEREOSELECTIVE SYNTHESIS OF CHIRAL AMINES | 1990 |
|
RU2116347C1 |
METHOD OF ENANTIOMERIC ENRICHMENT OF A MIXTURE CONSISTING OF TWO ENANTIOMERIC CHIRAL AMINES | 1990 |
|
RU2087536C1 |
METHOD OF L-2-AMINO-4-(HYDROXYMETHYLPHOSPHINYL)-BUTYRIC ACID PREPARATION | 0 |
|
SU1731067A3 |
DRINKING COMPOSITION CONTAINING MONATIN AND METHODS OF ITS PRODUCTION | 2004 |
|
RU2380989C2 |
SYSTEM OF COENZYME REDUCTION, SET FOR ENZYMATIC ASSAY OF CONCENTRATION OF ANALYZED SUBSTANCE AND ENZYMATIC METHOD OF ASSAY OF CONCENTRATION OF ANALYZED SUBSTANCE | 1996 |
|
RU2184778C2 |
METHOD FOR PREPARING CHIRAL AMINE | 1999 |
|
RU2213142C2 |
OBTAINING 1,4-DIAMINOBUTANE | 2010 |
|
RU2577967C2 |
METHODS FOR PRODUCTION OF GLUTAMATE (VARIANTS) AND MONATIN | 2002 |
|
RU2280078C2 |
METHOD OF INDOLE-3-PYRUVIC ACID AND ITS DERIVATIVES PRODUCTION | 2006 |
|
RU2325442C2 |
D-AMINO ACID TRANSAMINASE ENZYME FROM HALISCOMENOBACTER HYDROSSIS WITH EXTENDED SUBSTRATE SPECIFICITY | 2023 |
|
RU2824015C1 |
Authors
Dates
2006-04-27—Published
2000-03-30—Filed