METHOD OF STEREOSELECTIVE SYNTHESIS OF CHIRAL AMINES Russian patent published in 1998 - IPC

Abstract RU 2116347 C1

FIELD: organic chemistry, biotechnology. SUBSTANCE: method involves interaction of enzyme omega-aminoacid transaminase with ketone in the presence of amino-group donor being the latter is used at significant molar excess. Ketone and amino-group donor are interacted with the whole cells of microorganism that produce omega-aminoacid transaminase, or with an enzyme aqueous solution, or with enzyme immobilized on carrier. Method can be used in chemical technology, in production of pharmaceutical and agrochemical preparations. Method provides the preferential stereoselective synthesis of specific chiral amine form at increased yield. EFFECT: improved method of synthesis, increased yield of the end product. 6 cl, 1 tbl

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RU 2 116 347 C1

Authors

Dehvid I.Sterling

Ehndrju L.Zitlin

Dzhordzh V.Mehtchem

Dates

1998-07-27Published

1990-06-21Filed