FIELD: biotechnology, biochemistry. SUBSTANCE: method involves usage of 2-aminopropane as a donor of amino-group in stereoselective synthesis of chiral amine from ketone using transaminase. In part, (S)-1-methoxy-2-aminopropane is prepared by contacting methoxyacetone with transaminase in the presence of 2- aminopropane. Reaction is carried out up to the significant conversion of methoxyacetone to (S)-1-methoxy-2-aminopropane and conversion of 2-aminopropane to acetone. Then (S)-1-methoxy-2- aminopropane is isolated. Method provides reduction of energy and working consumptions and enhanced yield of chiral amine. EFFECT: improved preparing method. 3 cl, 5 ex
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Number |
| METHOD OF ENANTIOMERIC ENRICHMENT OF A MIXTURE CONSISTING OF TWO ENANTIOMERIC CHIRAL AMINES |
1990 |
- Dehvid I. Sterling[Gb]
- Ehndrju L. Zitlin[Gb]
- Dzhordzh V.Mehtchem[Us]
|
RU2087536C1 |
| METHOD OF STEREOSELECTIVE SYNTHESIS OF CHIRAL AMINES |
1990 |
- Dehvid I.Sterling
- Ehndrju L.Zitlin
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|
RU2116347C1 |
| METHOD FOR PREPARING L-PHOSPHINOTRICINE BY ENZYMATIC TRANSAMINATION BY USING ASPARTIC ACID |
2000 |
|
RU2275428C2 |
| CHEMICAL PROCESS FOR PREPARING SPIROINDOLONES AND INTERMEDIATES THEREOF |
2013 |
- Krou Majkl
- Folks Majkl
- Francheze Dzhankarlo
- Grimle Dominik
- Kyusters Ernst
- Laumen Kurt
- Li Yunchzhun
- Lin Chansyue
- Nazor Jovana
- Rukh Tomas
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- Sun Shivej
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| NEW METHOD AND NEW INTERMEDIATE COMPOUNDS |
2016 |
- Kleinbeck-Riniker, Florian Karl
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- Schlama, Thierry
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- Allmendinger, Thomas
- Wietfeld, Bernhard
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RU2769445C2 |
| METHOD AND INTERMEDIATE COMPOUNDS FOR PREGABALINE PRODUCTION |
2014 |
- Debarge Sebastien
- Erdman David Thomas
- O'Neill Padraig Mary
- Kumar Rajesh
- Karmilowicz Michael John
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RU2628298C2 |
| METHOD FOR ENANTIOMERIC ENRICHMENT OF MIXTURE OF D- AND L-TREO-2-AMINO-3-HYDROXY-3-PHENYL PROPIONIC ACIDS, OR DERIVATIVES THEREOF, OR SALTS THEREOF |
1992 |
- Ehndrju L.Zejtlin
- Muppala S.Radzhu
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RU2112805C1 |
| METHOD FOR DETERMINATION OF ENANTIOMERIC EXCESS OF CHIRAL COMPOUNDS (VERSIONS) |
2015 |
- Rastorguev Aleksandr Aleksandrovich
- Tarasevich Arkadij Viktorovich
- Snytnikov Valerij Nikolaevich
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RU2610352C1 |
| N-ALKYLCARBONYLAMINOACID ETHERS AND N-ALKYLCARBONYLAMINOLACTONS AND APPLICATION THEREOF |
2006 |
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RU2417218C2 |
| 2-(2-AMINO-1,6-DIHYDRO-6-OXOPURIN-9-YL)METOXY-3-HYDROXY- 1-PROPANYL-L-VALINATE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION AND HYDROXY AND/OR AMINO PROTECTED 2-(2- AMINO-1,6-DIHYDRO-6-OXOPYRIN-9-YL) METHOXY-3-HYDROXY-1- PROPANYL-L-VALINATE |
1995 |
- Dzhon Dzh.Nestor
- Skott V.Vombl
- Khans Maag
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RU2133749C1 |
