FIELD: pharmacy, chemical technology.
SUBSTANCE: invention relates to a method for separation of paclitaxel from cefalomannin. Method involves preparing the parent material comprising paclitaxel and cefalomannin, dissolving the parent material in solvent of the following formula: 
wherein R1 means hydrogen atom or methyl; R2 means alkyl or arylalkyl group comprising from 4 to 7 carbon atoms to form a mixture. Then this mixture is subjected for column chromatography in column filled with silica gel to obtain eluated fraction of paclitaxel, eluated fraction of cefalomannin and a residue followed by separating drying fractions of paclitaxel and cefalomannin to obtain separated crystalline forms of paclitaxel and cefalomannin, respectively. Invention provides simplifying process.
EFFECT: improved method for separating.
8 cl, 1 tbl, 2 ex
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