METHOD OF PRODUCING PACLITAXEL FROM Taxus GENUS PLANTS Russian patent published in 2009 - IPC C07D305/14 

Abstract RU 2373198 C2

FIELD: chemistry.

SUBSTANCE: plant material from paclitaxel-containing plants is obtained first. Paclitaxel is then extracted from the plant material. Paclitaxel is subsequently extracted from the paclitaxel extract using a series of column chromatography steps to obtain at least one fraction which contains paclitaxel. Paclitaxel in the fraction obtained from column chromatography steps is crystallised.

EFFECT: using these methods, highly pure paclitaxel can be efficiently produced from different types of yew plants or its parts, containing paclitaxel independent of paclitaxel content.

47 cl, 1 dwg, 2 ex

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RU 2 373 198 C2

Authors

Gabetta Bruno

Tsini Dzhanfranko

Dates

2009-11-20Published

2005-06-24Filed