DERIVATIVES OF TRIARYL-CONTAINING ACIDS AS OF PPAR RECEPTOR LIGANDS Russian patent published in 2006 - IPC C07D263/32 C07D277/24 C07D261/08 C07D271/06 A61K31/33 A61K31/559 A61P43/00 

Abstract RU 2278860 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to new compounds of the following formulae:

and , and to a pharmaceutical composition possessing the PPAR-ligand binding activity and comprising the indicated compound, and a pharmaceutically acceptable vehicle. Also, invention relates to a method for treatment of patient suffering with physiological disorder that can be modulated with the compound possessing the PPAR-ligand binding activity. Method involves administration to the patient the pharmaceutically effective dose of indicated compound or its pharmaceutically acceptable salt.

EFFECT: valuable medicinal properties of compounds and pharmaceutical composition.

10 cl, 1 tbl, 104 ex

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RU 2 278 860 C2

Authors

Dzhejjosi Zaid

Makgikhan Dzherard M.

Kelli Majkl F.

Labodin'Er Richard F.

Zhang Litao

Kolfild Tomas Dzh.

Minnikh Anne

Bobko Mark

Morris Robert

Groneberg Robert D.

Makgarri Dehniel G.

Dates

2006-06-27Published

2000-04-28Filed