METHOD FOR PRODUCTION OF FLUORINATED KETONE Russian patent published in 2006 - IPC C07C49/167 C07C49/463 C07C45/54 C07D319/06 C07B39/00 

FIELD: organic chemistry.

SUBSTANCE: invention relates to method for production of fluorinated ketone of general formula 5 . Claimed method includes reaction of compound of formula 3 , containing at least 30 wt.% of fluorine with fluorine in liquid phase, containing solvent selected from group comprising perfluoroalkane, perfluorinated ester, perfluorinated polyether, chlorofuorohydrocarbon, chlorofluoropolyether, perfluoroalkylamine, inert liquid, compound of formula 2 , compound of formula 6 to produce compound of formula 4 , followed by dissociation of ester bond in formula 4 in presence of KF, NaF or activated carbon without solvent. In formulae: R^A represents, optionally containing ether-forming oxygen atom, wherein each of said groups contains C₁-C₁₀ carbon atoms; R^AF represents C₁-C₁₀-perfluorenated R^A group; R^B represents alkyl optionally containing ether-forming oxygen atom, partially halogenated alkyl, optionally containing ether-forming oxygen atom, wherein each of said groups contains C₁-C₁₀ carbon atoms; R^BF represents C₁-C₁₀-perfluorenated R^B group; R^C and R^CF groups are identical ones and each R^C and R^CF contains C₂-C₁₀ carbon atoms and represents perfluorenated alkyl optionally containing ether-forming oxygen atom, partially halogenated alkyl, optionally containing ether-forming oxygen atom or R^A and R^B together form alkylene group optionally containing ether-forming oxygen atom, partially halogenated alkylene, optionally containing ether-forming oxygen atom, wherein each abovementioned group contains C₃-C₆ carbon atoms; each R^AF and R^BF are perflurenated R^A and R^B groups containing C₃-C₆ carbon atoms; groups are identical ones and each R^C and R^CF contains C₂-C₁₀ carbon atoms and represents perfluorenated alkyl optionally containing ether-forming oxygen atom, partially halogenated alkyl, optionally containing ether-forming oxygen atom. Method of present invention provides fluorinated ketone production with 71-96 % yield. Some intermediates of formula 3 also are described.

EFFECT: method for fluorinated ketone production with increased yield.

10 cl, 5 ex