FIELD: medicine, pharmacy.
SUBSTANCE: invention describes an orally administrated liquid composition used in treatment of respiratory diseases and comprising from 2% to 40% of guaifenesin and a filling agent comprising from 5% to 25% of polyoxyalkylene block-copolymer, from 30% to 90% of hydrophilic solvent, and from 5% to 45% of water. The composition shows high physical stability in delivery of the concentrated doses of pharmaceutically active component, in particular, the active component doesn't show precipitation from solution for the prolonged times. Also, the composition remains in a liquid form in the mouth cavity that provides the effect of the pharmaceutically active agent of the composition on large areas in the mouth cavity mucosa.
EFFECT: enhanced effectiveness and valuable medicinal properties of agent.
6 cl, 16 tbl, 1 dwg, 16 ex
