TREATMENT OF HERPETIC NEUROLOGICAL VIRAL DISEASES BY USING 1,4-DIHYDROPYRIDINE BLOCKERS OF CALCIUM CHANNELS Russian patent published in 2006 - IPC A61K31/44 A61K31/50 A61K31/52 A61K31/435 A61K31/495 A61P25/00 A61P31/12

Abstract RU 2281099 C2

FIELD: medicine, neurology, virology.

SUBSTANCE: invention relates to treatment of neurological diseases caused by herpes virus, such as Bell's paralysis, Hunt's disease, herpetic encephalitis accompanying with damage of cerebral nerves. Invention involves using 1,4-dihydropyridine blockers of calcium channels, such as felodipine, nifedipine, nimodipine, nisodipine being taken preferably in combination with herpes virus antagonist. Invention provides repairing damaged cerebral nerves by topical expanding arteriols and recovery of local microcirculation based on specific competitive interaction of definite groups of calcium blockers of 1,4-dihydropyridine type with vasoconstrictor endothelin.

EFFECT: enhanced effectiveness of treatment.

47 cl, 2 dwg, 1 ex

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RU 2 281 099 C2

Authors

Zik Govard

Dates

2006-08-10—Published

2000-11-21—Filed