FIELD: medicine.
SUBSTANCE: pharmaceutical composition for making tableted dosage form with modified release for oral administration of calcium channel blocker-felodipine contains felodipine or its pharmaceutically acceptable salt, a carrier for modified release and a hydration gel accelerator. The carrier for modified release is a salt of alginic acid with an alkali metal. The hydration gel accelerator is hydroxypropyl methylcellulose.
EFFECT: provision for relatively fast (during several hours) release of felodipine, with simultaneous prolonged retention of its concentration in blood plasma at a stable high level, and is characterised by low cost of production.
20 cl, 1 dwg, 2 tbl, 3 ex
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