METHOD FOR PRODUCTION OF HEPATOTHROPIC ARTICHOKE EXTRACT-BASED POLYPHENOL PHARMACEUTICAL AGENT Russian patent published in 2006 - IPC A61K36/38 A61K127/00 A61P1/16 

Abstract RU 2281112 C2

FIELD: pharmaceutical industry, in particular production of hepatothropic drug based on artichoke polyphenols.

SUBSTANCE: claimed method includes breakage of fresh artichoke leaves, treatment with hot steam for certain time; two-step extraction with hot water under specific conditions, extract separation from solvent cake, concentration of artichoke aqueous extract in vacuum to produce syrup-like extract. Obtained syrup-like extract is blended with filler, detacher and lubricant in specific component ratio.

EFFECT: method of increased yield; biologically active substances of improved stability; reduced raw material and extractant consumption; capsulated hepatothropic drug with high therapeutic activity and prolonged storage time.

10 cl, 8 ex

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RU 2 281 112 C2

Authors

Dorovskoj Aleksandr Viktorovich

Khorunzhij Gennadij Gennad'Evich

Zubchenko Tamara Nikolaevna

Dolgalenko Ljudmila Grigor'Evna

Matveeva Tat'Jana Viktorovna

Dranik Irina Leonidovna

Dates

2006-08-10Published

2004-10-08Filed