FIELD: pharmaceutical industry, in particular production of hepatothropic drug based on artichoke polyphenols.
SUBSTANCE: claimed method includes breakage of fresh artichoke leaves, treatment with hot steam for certain time; two-step extraction with hot water under specific conditions, extract separation from solvent cake, concentration of artichoke aqueous extract in vacuum to produce syrup-like extract. Obtained syrup-like extract is blended with filler, detacher and lubricant in specific component ratio.
EFFECT: method of increased yield; biologically active substances of improved stability; reduced raw material and extractant consumption; capsulated hepatothropic drug with high therapeutic activity and prolonged storage time.
10 cl, 8 ex
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Authors
Dates
2006-08-10—Published
2004-10-08—Filed