FIELD: organic chemistry, chemical technology, medicine, pharmacy.
SUBSTANCE: invention relates to the improved method for synthesis of indane-1,3-dicarboxylic acid of the formula (I): wherein R1 and R2 represents hydrogen atom. Method involves hydrolysis of compound of the formula: wherein R1 and R2 represent hydrogen atom in the presence of acidic or basic catalyst. Synthesized compound represents an intermediate substance that can be used in synthesis of aryl-condensed azapolycyclic compounds used as agents in treatment of neurological and psychiatric disorders in medicine.
EFFECT: improved preparing method, valuable medicinal properties of compounds.
9 cl, 2 sch, 3 ex
Authors
Dates
2006-08-27—Published
2003-11-07—Filed