FIELD: chemistry.
SUBSTANCE: invention relates to novel method of obtaining intermediate compounds, used for obtaining NEP inhibitors or their prodrugs, in particular NEP inhibitors, containing structure of γ-amino-δ-biphenyl-α-methylalkane acid or acid ester, such as ethyl ester of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino (2R)methylbutanic acid or its salt.
EFFECT: increase of method efficiency.
15 cl, 1 dwg, 2 tbl, 8 ex
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