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2 282 647

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IPC

C09B47/32(2006-01-01)

C07D487/22(2006-01-01)

C07F3/06(2006-01-01)

C07F5/06(2006-01-01)

A61K31/409(2006-01-01)

(21) (22)

Application

2005116329/04, 2005-05-31

(24)

Start date

2005-05-31

(22)

Actual filing date

2005-05-31

(45)

Published

2006-08-27

(72)

Inventor

Vorozhtsov Georgij NikolaevichKalija Oleg LeonidovichKuznetsova Nina AleksandrovnaKuz'Min Sergej GeorgievichKucherov Aleksandr GeorgievichLapchenko Aleksandr SergeevichLuzhkov Jurij MikhajlovichLuk'Janets Evgenij AntonovichNegrimovskij Vladimir MikhajlovichSlivka Ljudmila KonstantinovnaStrakhovskaja Marina GlebovnaJuzhakova Ol'Ga AlekseevnaJakubovskaja Raisa Ivanovna

(73)

Holder

Federal'Noe Gosudarstvennoe Unitarnoe Predprijatie Nauchnyj Tsentr Institut Organicheskikh Poluproduktov I Krasitelej"

PHOTOSENSITIZING AGENTS FOR ANTIMICROBIAL PHOTODYNAMIC THERAPY Russian patent published in 2006 - IPC C09B47/32 C07D487/22 C07F3/06 C07F5/06 A61K31/409

Abstract RU 2282647 C1

FIELD: medicine, in particular photosensitizing agents for antimicrobial photodynamic therapy.

SUBSTANCE: invention relates to new photosensitizing agents for antimicrobial photodynamic therapy namely cationic phthalocyanines of general formula MPc(CH₂X)_nCl_n, wherein Pc is phthalocyanine rest C₃₂H₁₆N₈; M is Zn, AlY; n = 6-8; X is Y is Cl, OH, OSO₃H. Claimed agents is characterized by wide range of antimicrobial activity. Single complex action of nontoxic in darkness micromolar (up to 2.0 muM) concentration thereof and low dose of red irradiation make it possible to produce high inactivation levels (up to 97-99 %) both gram-negative bacteria and yeast fungi of genus Candida.

EFFECT: improved agents for treatment of various severe complications of inflammation diseases.

3 dwg, 13 ex, 2 tbl

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RU 2 282 647 C1

Authors

Vorozhtsov Georgij Nikolaevich

Kalija Oleg Leonidovich

Kuznetsova Nina Aleksandrovna

Kuz'Min Sergej Georgievich

Kucherov Aleksandr Georgievich

Lapchenko Aleksandr Sergeevich

Luzhkov Jurij Mikhajlovich

Luk'Janets Evgenij Antonovich

Negrimovskij Vladimir Mikhajlovich

Slivka Ljudmila Konstantinovna

Strakhovskaja Marina Glebovna

Juzhakova Ol'Ga Alekseevna

Jakubovskaja Raisa Ivanovna

Dates

2006-08-27—Published

2005-05-31—Filed