NEW SUBSTANCES BINDING TO HELICOBACTER PILORI AND USES THEREOF Russian patent published in 2006 - IPC A61K31/702 A61P1/04 

Abstract RU 2283115 C2

FIELD: medicine, pharmaceuticals.

SUBSTANCE: disclosed are agent of formula I binding to Helicobacter pilori ex vivo and substance based thereon, as well as pharmaceutical composition, food supplement and method for identification of bacterial adhesine. Claimed substance comprises agent of formula 1 and carrier. In particular substance includes Galβ3GlcNAc. Said agent may by conjugated with oligosaccharide or ceramide. Claimed agent represents specifically binding epitope of lactotetraose or lactotetraosyl ceramide (Galβ3GlcNAcβ3Galβ-4Glc1Cer) having lactotetraosyl ceramide sfingolipide-like activity, and is useful in typing of Helicobacter pilori, in Helicobacter pilori binding inhibition and in identification of bacterial adhesine.

EFFECT: new substances for binding to Helicobacter pilori.

18 cl, 13 dwg, 3 tbl

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RU 2 283 115 C2

Authors

Karlsson Karl-Anders

Leonardsson Irene

Teneberg Susann

Ongstrem Jonas

Dates

2006-09-10Published

2000-12-15Filed