FIELD: gene engineering, virology, veterinary.
SUBSTANCE: invention relates to DNA-vaccine against canine distemper virus (CDV). Said vaccine includes at least one DNA-plasmid and cationic lipid containing ammonium salt of formula represented in claim 1 as adjuvant. DNA-plasmid also contains and expresses in host-cells nucleotide sequence encoding CVD immunogene. Nucleotide sequence contains deletion of site, encoding transmembrane domain. Polyvalent vaccine, containing such DNA-vaccine and immunogenic composition containing such DNA-plasmid also are disclosed.
EFFECT: new vaccine for vaccination of dogs against CDV.
41 cl, 28 dvg, 3 tbl, 14 ex
| Title |
Year |
Author |
Number |
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2002 |
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|
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| DNA, PROTEINS, EXPRESSING VECTORS AND IMMUNOGENIC, VACCINE, AND STIMULATING COMPOSITIONS, CONTAINING HORSE GM-CSF |
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|
RU2279476C2 |
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2011 |
- Odonne Zhan-Kristof
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|
RU2567337C2 |
| RECOMBINANT BLUETONGUE VACCINE |
2007 |
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|
RU2446823C2 |
| CANINE RABIES VACCINE (VARIANTS), METHOD FOR VACCINATION (VARIANTS), A KIT FOR VACCINATION (VARIANTS) |
1997 |
- Odonne Zhan-Kristof
- Bushardon Annabell'
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|
RU2319504C2 |
| DNA PLASMIDS SHOWING HIGH EXPRESSION AND STABILITY |
2007 |
|
RU2456346C2 |
| FORMULA OF FELINE VACCINE |
2002 |
- Odonne Zhan-Kristof
- Bushardon Annabell'
- Bodju Filipp
- Riv'Er Mishel'
|
RU2312676C2 |
| HYBRID PROTEIN, HYBRID GENE, METHOD OF PREPARING A HYBRID PROTEIN, VACCINE AGAINST UPPER RESPIRATORY WAY VIRAL DISEASE, BACULOVIRAL EXPRESSION VECTOR (VARIANTS) |
1993 |
- Mishel Kh.Klejn
- Run-Pan Du
- Meri E.Ehvazishin
|
RU2123047C1 |
| VACCINE FORMULA AGAINST BOVINE RESPIRATORY PATHOLOGIES |
2002 |
- Odonne Zhan-Kristof
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|
RU2305560C2 |
| RECOMBINANT VIRUS EXPRESSING FOREIGN DNA ENCODING FELINE CD80, FELINE CTLA-4 OR FELINE CD86 AND ITS APPLYING |
1999 |
- Uinslou Barbara Dzh.
- Kokran Mark D.
|
RU2244006C2 |
