COMBINATION THERAPY WITH ANTITUMOR ALKALOID Russian patent published in 2021 - IPC A61K31/4995 A61K31/704 A61K45/06 A61P35/00 

FIELD: medicine.

SUBSTANCE: set of inventions relates to medicine, in particular to oncology, and is intended for treating cancer. The method for treating cancer involves introducing a therapeutically effective quantity of PM01183 or a pharmaceutically acceptable salt thereof to a patient who needs said treatment in a synergistic combination with a therapeutically effective quantity of an anticancer antibiotic. The anticancer antibiotic is selected from daunorubicin, doxorubicine, mitomycin C and actinomycin D. The cancer to be treated is selected from lung cancer, sarcoma, malignant melanoma, prostate cancer, pancreatic cancer, stomach cancer, ovarian cancer, hepatoma, breast cancer, colorectal cancer, kidney cancer, brain cancer, leukemia and lymphoma. It also ensures the use of PM01183 or its pharmaceutically acceptable salt in a synergistic combination with an anticancer antibiotic for the treatment of cancer and the use of PM01183 or its pharmaceutically acceptable salt in a synergistic combination with an anticancer antibiotic in production of a drug for the treatment of cancer.

EFFECT: use of set of inventions enables increasing efficiency of cancer treatment.

15 cl, 296 dwg, 26 tbl, 21 ex