PHARMACEUTICAL COMPOSITION COMPRISING 5HT1-RECEPTOR AGONIST Russian patent published in 2006 - IPC A61K31/405 A61K9/22 A61K9/46 A61P25/06 

FIELD: medicine, pharmacy.

SUBSTANCE: invention relates to a pharmaceutical composition used in migraine treatment as a solid dosed medicinal formulation for the peroral administration that comprises 5-HT₁-agonist sumatriptan or its pharmaceutically active salt or solvate as an active component (in the amount 20-150 mg of sumatriptan as a base) and a main component of a carbonated pair, a loosening agent and an insoluble excipient wherein the amount of the main component id from about 5 to about 50%% by mass, the amount of a loosing component is from about 0.5 to about 10% by mass, and the amount of insoluble excipient is from about 35 to about 80% by mass. Also, invention relates to using the proposed composition in migraine treatment. The composition can be used orally as a whole and provides the curative effect after rapid absorption typical for carbonated compositions.

EFFECT: improved and valuable medicinal and pharmaceutical properties of composition.

8 cl, 6 tbl, 3 dwg, 16 ex